The Curse Killing Blood Vase, as long as you obtain the blood of the person you want to kill, can curse and kill them from thousands of miles away.
But the person targeted must not have too large a disparity in cultivation with the user; the greater the disparity, the lower the chance of successful cursing and killing. If the cursing and killing fails, the user will die on the spot.
In the Cyan Mountain Sword Sect, when Chu Nan was at the ninth level of the Spirit Pill Realm, he killed Song Zhen, who was at the second level of the Yang Wheel.
Now, although Chu Nan is at the fifth level of the Yang Wheel, his target for the curse is Zhang Mingxuan, who is at the ninth level of the Yang Wheel, a challenge far greater than Song Zhen.
He understands that this curse killing involves extreme risk, but without killing Zhang Mingxuan, Chu Nan cannot leave this mountain range.
As the blood drips in, the bloody glow of the Curse Killing Blood Vase grows more intense.