The reason Ash had decided to enter inside the Hollow Mother was because of the information provided by the Whisperer.
According to him, the Hollow Mother, as powerful as it was known to be, possessed a terrifying ability to control the minds of others, twisting their will until they became nothing but obedient puppets. It only needed time for that influence to take root. However, in exchange for such an overwhelming ability, it sacrificed its mobility entirely.
It could not move from its spot, remaining anchored like a monstrous, living growth. For protection, it relied on the people it controlled or its enormous tentacles that acted like limbs, lashing out at anything that came close. Other than that, its natural defenses were formidable, and its ability to heal was exceptionally fast. This was why killing it from the outside was considered nearly impossible.