After Lucien's attack on the Katsuragi-hen clan, his grandmother was made aware of his presence. Initially, she thought he is dead, but seeing him alive, made her chuckle it delight. Although Lucien might not be aware, she played a part in messing with his life.
As a shaman of her stage, unlike Tsito, she can enter the spirit realm. Although she disliked Akane for failing to live up to her plans, she dislikes Lucien more, because of what he is.
Just like Yotram, she can feed on people's souls to increase her strength. However, when she tried to enter Lucien to feed on him, she got rejected by his body. In fact, every time she tried to possess him, she ended up getting hurt.
In the end, she caused problems for him, to weaken his mind. However, that only strengthened him more, making everytime she tried to possess him, more painful than the last. As a last resort, she sent illnesses and cursed him, using Deuce's blessing.
