In the previous 1665 dungeon, Xu Yun received a conspicuous hint about the Five Dynasties' imidacloprid formula:
[This is good stuff, but truly mastering it won't be easy].
Thus, the entire formula is not a fool-proof one-click guide but provides some directions and structural expression diagrams. Many aspects require Xu Yun to personally work and think to solve it—like the previous pheromone, for instance, or the targeted binding method from the fourth to fifth generation.
To put it simply, you cannot have something for nothing.
However, compared to the cyclization breakthrough from the third to fourth generation, the difficulty from the fourth to fifth generation is undoubtedly much smaller, meaning the leap isn't quite as large.
Fourth-generation determines the structure, fifth-generation supplements the functionality, and the former is the key point of qualitative change.